K M Gaensler

Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin

Chad May, Stefano Rivella, J Callegari et al. · Nature · 2000 · 566 citations

Biochemistry, Hematology, Immunology +7

Aerosol gene delivery in vivo.

Roscoe Stribling, Elisa Brunette, Denny Liggitt et al. · Proceedings of the National Academy of Sciences · 1992 · 272 citations · Full text

Asthma, Nanomedicine, Cat Activity +13

Promoterless gene targeting without nucleases ameliorates haemophilia B in mice

Adi Barzel, Nicole K. Paulk, Yun Shi et al. · Nature · 2014 · 261 citations · Full text

Knockout Mouse, Transcriptional Regulation, Genetics +7

Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.

Andrew C. Perkins, K M Gaensler, Stuart H. Orkin · Proceedings of the National Academy of Sciences · 1996 · 147 citations · Full text

Targeted Gene Disruption, Transcriptional Regulation, Developmental Biology +15

Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice.

K M Gaensler, Masanori Kitamura, Yuet Wai Kan · Proceedings of the National Academy of Sciences · 1993 · 137 citations

Sequential Expression, Genetics, Genomic Mechanism +25