Charles D. Jones

Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride (LY 156758), a remarkably effective estrogen antagonist with only minimal intrinsic estrogenicity

Charles D. Jones, Mary G. Jevnikar, Andrew Pike et al. · Journal of Medicinal Chemistry · 1984 · 282 citations

Molecular determinants of tissue selectivity in estrogen receptor modulators

Timothy A. Grese, James P. Sluka, Henry U. Bryant et al. · Proceedings of the National Academy of Sciences · 1997 · 242 citations · Full text

Estrogen Receptor, Gynecology, Raloxifene Analogs +16

Structure−Activity Relationships of Selective Estrogen Receptor Modulators:  Modifications to the 2-Arylbenzothiophene Core of Raloxifene

Timothy A. Grese, Stephen Cho, Don R. Finley et al. · Journal of Medicinal Chemistry · 1997 · 175 citations · Full text

Gynecology, Raloxifene Analogs, Pharmacotherapy +23

Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase

Charles D. Jones, James E. Audia, David E. Lawhorn et al. · Journal of Medicinal Chemistry · 1993 · 90 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +11

Synthesis and antiestrogenic activity of [3,4-dihydro-2-(4-methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone, methanesulfonic acid salt

Charles D. Jones, Tulio Suarez, Eddie H. Massey et al. · Journal of Medicinal Chemistry · 1979 · 49 citations · Full text

Medicinal Chemistry, Derivative (Chemistry), Natural Sciences +10