Leonard A. McDonald

Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors

Leonard A. McDonald, Laurel R. Barbieri, Guy T. Carter et al. · Journal of the American Chemical Society · 2002 · 203 citations

Medicine, Microbiology, Pharmacology +16

Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities

Benfang Helen Ruan, Kevin Pong, Flora Jow et al. · Proceedings of the National Academy of Sciences · 2007 · 112 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16

Inhibition of Topoisomerase II Catalytic Activity by Pyridoacridine Alkaloids from a Cystodytes sp. Ascidian: A Mechanism for the Apparent Intercalator-Induced Inhibition of Topoisomerase II

Leonard A. McDonald, Glenn S. Eldredge, Louis R. Barrows et al. · Journal of Medicinal Chemistry · 1994 · 103 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Aleksandra Wlodek, Steve Kendrew, Nigel J. Coates et al. · Nature Communications · 2017 · 95 citations · Full text

Engineering, Biotechnology, Molecular Biology +17

Discovery and Assembly-Line Biosynthesis of the Lymphostin Pyrroloquinoline Alkaloid Family of mTOR Inhibitors in Salinispora Bacteria

Akimasa Miyanaga, Jeffrey E. Janso, Leonard A. McDonald et al. · Journal of the American Chemical Society · 2011 · 85 citations

Pharmacy, Biochemistry, Molecular Biology +17