J Lewthwaite

Inhibition of interleukin-1-induced synovitis and articular cartilage proteoglycan loss in the rabbit knee by recombinant human interleukin-1 receptor antagonist

Brian E. Henderson, Robert C. Thompson, Tim Hardingham et al. · Cytokine · 1991 · 115 citations

Medicine, Immunology, Orthopedic Surgery +17

Short-term rigid and flaccid paralyses diminish growth of embryonic chick limbs and abrogate joint cavity formation but differentially preserve pre-cavitated joints.

Anne C. Osborne, Katherine J. Lamb, J Lewthwaite et al. · PubMed · 2002 · 109 citations

Life Sciences, Developmental Biology, Biomechanics +16

Age-related Changes in the Response of Human Articular Cartilage to IL-1α and Transforming Growth Factor-β (TGF-β)

Mark S. Hickery, Michael T. Bayliss, Jayesh Dudhia et al. · Journal of Biological Chemistry · 2003 · 65 citations · Full text

Life Sciences, Cell Biology, Immunology +15

The effect of recombinant human interleukin 1 receptor antagonist on the induction phase of antigen induced arthritis in the rabbit.

J Lewthwaite, SM Blake, Tim Hardingham et al. · PubMed · 1994 · 52 citations

Medicine, Immunology, Pathobiology +17

A mechanism underlying the movement requirement for synovial joint cavitation

Gary P. Dowthwaite, Carl R. Flannery, J. Flannelly et al. · Matrix Biology · 2003 · 48 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +13