Ellen Marie Straarup

LNA-mediated microRNA silencing in non-human primates

Joacim Elmén, Morten Lindow, Sylvia Schütz et al. · Nature · 2008 · 1.6K citations

Life Sciences, Genetics, Molecular Biology +9

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

Joacim Elmén, Morten Lindow, Asli Silahtaroglu et al. · Nucleic Acids Research · 2007 · 671 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15

Silencing of microRNA families by seed-targeting tiny LNAs

Susanna Obad, Camila O. dos Santos, Andreas Petri et al. · Nature Genetics · 2011 · 628 citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

Ellen Marie Straarup, Niels Fisker, Maj Hedtjärn et al. · Nucleic Acids Research · 2010 · 245 citations · Full text

Pharmacy, Biochemistry, Pharmacology +17

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

Jesper Worm, Jan Stenvang, Andreas Petri et al. · Nucleic Acids Research · 2009 · 194 citations · Full text

Life Sciences, Immunology, Molecular Biology +17