Maj Hedtjärn

LNA-mediated microRNA silencing in non-human primates

Joacim Elmén, Morten Lindow, Sylvia Schütz et al. · Nature · 2008 · 1.6K citations

Lna-mediated Microrna, Genetics, Microrna Detection +5

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

Joacim Elmén, Morten Lindow, Asli Silahtaroglu et al. · Nucleic Acids Research · 2007 · 669 citations · Full text

Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

C.A. Stein, Jens Bo Hansen, Johnathan C. Lai et al. · Nucleic Acids Research · 2009 · 376 citations · Full text

Engineering, Molecular Biology, Gene Delivery +20

Interleukin-18 Involvement in Hypoxic–Ischemic Brain Injury

Maj Hedtjärn, Anna‐Lena Leverin, Kristina Eriksson et al. · Journal of Neuroscience · 2002 · 294 citations · Full text

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

Ellen Marie Straarup, Niels Fisker, Maj Hedtjärn et al. · Nucleic Acids Research · 2010 · 244 citations · Full text