Bill D. Roebuck

Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.

Thomas W. Kensler, Patricia A. Egner, Patrick M. Dolan et al. · PubMed · 1987 · 242 citations

Pharmacy, Pharmacology, Toxicology +14

Potent Protection against Aflatoxin-Induced Tumorigenesis through Induction of Nrf2-Regulated Pathways by the Triterpenoid 1-[2-Cyano-3-,12-Dioxooleana-1,9(11)-Dien-28-Oyl]Imidazole

Melinda S. Yates, Mi-Kyoung Kwak, Patricia A. Egner et al. · Cancer Research · 2006 · 189 citations

Medicine, Oncology, Pharmacology +13

Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.

Thomas W. Kensler, Patricia A. Egner, Nancy E. Davidson et al. · PubMed · 1986 · 167 citations

Pharmacy, Biochemistry, Toxicology +17

Protection against aflatoxin B1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry.

Bill D. Roebuck, Y L Liu, Adrianne E. Rogers et al. · PubMed · 1991 · 164 citations

Pharmacy, Pharmacology, Toxicology +16

Pancreatic carcinoma in azaserine-treated rats: Induction, classification and dietary modulation of incidence

Daniel S. Longnecker, Bill D. Roebuck, James D. Yager et al. · Cancer · 1981 · 119 citations

Medicine, Oncology, Pharmacology +17