J. B. Trepel

Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway.

M V Blagosklonny, Tim Schulte, P Nguyen et al. · PubMed · 1996 · 376 citations

Life Sciences, Cell Biology, Pharmacology +17

Transcriptional Activation of p21 WAF1/CIP1 by Apicidin, a Novel Histone Deacetylase Inhibitor

Jung-Sik Kim, Sun-Min Lee, Theresa Lee et al. · Biochemical and Biophysical Research Communications · 2001 · 52 citations

Life Sciences, Cancer Biology, Molecular Biology +15

Role of protein kinase C in the modulation of multidrug resistance: expression of the atypical gamma isoform of protein kinase C does not confer increased resistance to doxorubicin.

Shakeel Ahmad, J. B. Trepel, Shigeo Ohno et al. · Molecular Pharmacology · 1992 · 35 citations

Medicine, Oncology, Pharmacology +16

Folate Transport and the Modulation of Antifolate Sensitivity in a Methotrexate-Resistant Human Breast Cancer Cell Line

Katharine H. Dixon, J. B. Trepel, Simona Eng et al. · Cancer Communications · 1991 · 23 citations · Full text

Medicine, Oncology, Pharmacology +15

Rapid Turnover and Impaired Cell-Surface Expression of the Human Folate Receptor in Mouse L(tk-) Fibroblasts, a Cell-Line Defective in Glycosylphosphatidylinositol Tail Synthesis

Koong-Nah Chung, Steven Roberts, Cheol‐Hee Kim et al. · Archives of Biochemistry and Biophysics · 1995 · 12 citations

Life Sciences, Biochemistry, Cell Biology +8