Xin-Yan Pei

A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis

Shuang Chen, Yu Zhang, Liang Zhou et al. · Blood · 2014 · 99 citations · Full text

Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik

Shuang Chen, Liang Zhou, Yu Zhang et al. · Molecular and Cellular Biology · 2014 · 93 citations · Full text

Mitophagy, Apoptosis, Cell Death +18

Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF‐κB and Bim

Yun Dai, Shuang Chen, Li Wang et al. · British Journal of Haematology · 2011 · 63 citations

CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies

Shuang Chen, Yun Dai, Xin-Yan Pei et al. · Cancer Research · 2012 · 57 citations · Full text

Apoptosis, Immunology, Cell Death +18

Circumvention of Mcl-1-Dependent Drug Resistance by Simultaneous Chk1 and MEK1/2 Inhibition in Human Multiple Myeloma Cells

Xin-Yan Pei, Yun Dai, Jessica Felthousen et al. · PLoS ONE · 2014 · 32 citations · Full text

Hematological Malignancy, Simultaneous Chk1, Diminished Bim Expression +15