Matthew J. Wyvratt

(2<i>R</i>)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-<i>a</i>]pyrazin- 7(8<i>H</i>)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine:  A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Dooseop Kim, Liping Wang, Maria Beconi et al. · Journal of Medicinal Chemistry · 2004 · 808 citations · Full text

A new class of angiotensin-converting enzyme inhibitors

Arthur A. Patchett, Elbert E. Harris, Edward W. Tristram et al. · Nature · 1980 · 706 citations

Medicinal Chemistry, Medicine, Antihypertensive Therapy +5

A Nonpeptidyl Growth Hormone Secretagogue

Roy G. Smith, Kang Cheng, William R. Schoen et al. · Science · 1993 · 348 citations

Signal Transduction, Pituitary Gland, Biochemistry +9

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin.

Francis J. Dumont, Mary Jo Staruch, Sam L. Koprak et al. · The Journal of Experimental Medicine · 1992 · 253 citations · Full text

Immunotoxicology, Toxic Effects, Immunology +19

Human β3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides

Linda Brockunier, Emma R. Parmee, Hyun Ok et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 199 citations · Full text

Molecular Pharmacology, Medicine, Pharmacological Agent +5