Concepedia

F. Hofmann

FH

11

Publications

1.7K

Citations

11

H-Index

1991

Active since

Affiliations

École Polytechnique Fédérale de Lausanne(Current)

Novartis (Switzerland)

Dana-Farber Cancer Institute

F. Hofmann is an author at École Polytechnique Fédérale de Lausanne specializing in medicine, cell biology, and cell signaling.

Top concepts

MedicineCell BiologyCell SignalingSignal TransductionCell PhysiologyNatural SciencesMolecular BiologyPhysiologyBiochemistryPharmacology

Publications per year

1991–2016

11

Publications

11

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.

J M Wood, Guido Bold, Elisabeth Buchdunger et al. · PubMed · 2000 · 846 citations

Immunology, Oral Administration, Pharmacotherapy +20

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway.

F. Hofmann, Fabio Martelli, David M. Livingston et al. · Genes & Development · 1996 · 229 citations · Full text

Molecular Regulation, Cell Death, Molecular Biology +17

Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit.

F. Hofmann, David M. Livingston · Genes & Development · 1996 · 117 citations · Full text

Transcriptional Regulation, Differential Effects, Signal Transduction +12

The calmodulin-binding domain mediates the self-association of the plasma membrane Ca2+ pump.

Thomas Vorherr, F. Hofmann, Ernesto Carafoli · Journal of Biological Chemistry · 1991 · 112 citations · Full text

Proteinlipid Interaction, Calmodulin-stimulated Atpase Activity, Molecular Biology +20

Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia

Caroline Dafflon, Vanessa J. Craig, Hélène Méreau et al. · Leukemia · 2016 · 100 citations

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +8

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