Kevin Coleman

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Jing Lü, Yimin Qian, Martha Altieri et al. · Chemistry & Biology · 2015 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +6

Expression of engrailed proteins in arthropods, annelids, and chordates

Nipam H. Patel, Enrique Martı́n-Blanco, Kevin Coleman et al. · Cell · 1989 · 1K citations

Life Sciences, Biology, Molecular Biology +6

PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer

Kanak Raina, Jing Lü, Yimin Qian et al. · Proceedings of the National Academy of Sciences · 2016 · 827 citations · Full text

Medicine, Molecular Biology, Oncology +17

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2

Xiao-ding Peng, Pei-Zhang Xu, Mei-Ling Chen et al. · Genes & Development · 2003 · 826 citations · Full text

Medicine, Developmental Biology, Genetics +17

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ

Robert S. Garofalo, Stephen Orena, Kristina Rafidi et al. · Journal of Clinical Investigation · 2003 · 712 citations · Full text

Life Sciences, Endocrinology, Physiology +17