Andrew M. Schumacher

Chemical activation of the mechanotransduction channel Piezo1

Ruhma Syeda, Jie Xu, Adrienne E. Dubin et al. · eLife · 2015 · 743 citations · Full text

Natural Sciences, Biophysics, Cell Biology +17

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

Cheryl Carson, Pichai Raman, Jennifer Tullai et al. · PLoS ONE · 2015 · 109 citations · Full text

Medicine, Oncology, Pharmacology +15

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA

Kate Owen, Deyi Qiu, Juliano Alves et al. · Biochemical Journal · 2009 · 95 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury

Anastasia Velentza, Mark S. Wainwright, Magdalena Zasadzki et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133

Yahu A. Liu, Qihui Jin, Yefen Zou et al. · Journal of Medicinal Chemistry · 2020 · 77 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15