Ayşe Ufuk

Predicting Human Clearance of Organic Anion Transporting Polypeptide Substrates Using Cynomolgus Monkey: In Vitro–In Vivo Scaling of Hepatic Uptake Clearance

Tom De Bruyn, Ayşe Ufuk, Carina Cantrill et al. · Drug Metabolism and Disposition · 2018 · 50 citations · Full text

<i>In Vitro</i>and<i>in Silico</i>Tools To Assess Extent of Cellular Uptake and Lysosomal Sequestration of Respiratory Drugs in Human Alveolar Macrophages

Ayşe Ufuk, Frauke Assmus, Laura Francis et al. · Molecular Pharmaceutics · 2017 · 25 citations · Full text

In Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus Monkey

Ayşe Ufuk, Rachel E. Kosa, Hongying Gao et al. · Journal of Pharmacology and Experimental Therapeutics · 2018 · 22 citations

Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance

Norikazu Matsunaga, Ayşe Ufuk, Bridget L. Morse et al. · Drug Metabolism and Disposition · 2018 · 19 citations · Full text

In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383

Ayşe Ufuk, Graham Somers, J. Brian Houston et al. · Pharmaceutical Research · 2015 · 18 citations · Full text