Barbara O’Brien

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

Timothy F. Cloughesy, Aaron Mochizuki, Joey Orpilla et al. · Nature Medicine · 2019 · 1.4K citations

Medicine, Immunology, Oncology +17

Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages

John de Groot, Marta Peñas-Prado, Kristin Alfaro-Munoz et al. · Neuro-Oncology · 2019 · 166 citations · Full text

Medicine, Immunology, Oncology +17

Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease: phase 1 trial interim results

Isabella C. Glitza Oliva, Sherise D. Ferguson, Roland L. Bassett et al. · Nature Medicine · 2023 · 80 citations · Full text

Medicine, Oncology, Pharmacotherapy +17

Immunotherapy of Relapsed and Refractory Solid Tumors With Ex Vivo Expanded Multi-Tumor Associated Antigen Specific Cytotoxic T Lymphocytes: A Phase I Study

Amy B Hont, Carolina Colli Cruz, Robert Ulrey et al. · Journal of Clinical Oncology · 2019 · 79 citations · Full text

Life Sciences, Immunology, Oncology +17

Phase 1 lead‐in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma

Stefania Maraka, Morris D. Groves, Aaron Mammoser et al. · Cancer · 2018 · 68 citations · Full text

Medicine, Oncology, Pharmacology +15