Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.

Gabriele Missale, Roberto Bertoni, V. Lamonaca, +7

Journal of Clinical Investigation

ImmunologyChronic EvolutionPathologyChronic Viral PersistenceImmunotherapy +14

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

Antonio Bertoletti, Alessandro Sette, Francis V. Chisari, +5

Nature

T-regulatory CellImmunologyAntiviral ResponseCytotoxic EpitopesAntigen Processing +6

Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.

Carlo Ferrari, Amalia Penna, Antonio Bertoletti, +6

The Journal of Immunology

Adaptive Immune SystemImmunologyHepatitis BPathologyHbv Envelope Ag +17

Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen.

Amalia Penna, Francis V. Chisari, Antonio Bertoletti, +5

The Journal of Experimental Medicine

HistocompatibilityHbv CoreHla ImmunogeneticsImmunologyHepatitis B +17

Lamivudine Treatment Can Overcome Cytotoxic T–Cell Hyporesponsiveness in Chronic Hepatitis B: New Perspectives for Immune Therapy

Carolina Boni, Amalia Penna, Graham S. Ogg, +9

Hepatology

Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections

Antonio Bertoletti, Mario Milco D’Elios, Carolina Boni, +8

Gastroenterology

Autoimmune DiseaseHepatologyHepatitis CViral HepatitisT-regulatory Cell +11

HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen.

Antonio Bertoletti, Carlo Ferrari, F Fiaccadori, +6

Proceedings of the National Academy of Sciences

HistocompatibilityViral HepatitisHla ImmunogeneticsImmunologyHepatitis B +13

Long-lasting memory T cell responses following self-limited acute hepatitis B.

Amalia Penna, Marco Artini, A. Cavalli, +8

Journal of Clinical Investigation

Adaptive Immune SystemHumoral ResponseImmunologyHepatitis BPathology +18

T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections

Carlo Ferrari, A Valli, L. Galati, +7

Hepatology

ImmunologyProliferative ResponseAntigen ProcessingImmune SystemImmunotherapy +15

Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope.

Antonio Bertoletti, Antonio Costanzo, Francis V. Chisari, +7

The Journal of Experimental Medicine