Thomas F. Hendrickson

Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

F. MOHAMADI, Nigel G. J. Richards, Wayne C. Guida et al. · Journal of Computational Chemistry · 1990 · 3.8K citations

Natural Sciences, Chemistry, Biomolecular Modeling +13

Semianalytical treatment of solvation for molecular mechanics and dynamics

W. Clark Still, Anna Tempczyk, Ronald C. Hawley et al. · Journal of the American Chemical Society · 1990 · 3.7K citations

Natural Sciences, Chemistry, Computational Chemistry +16

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

David A. Matthews, Peter S. Dragovich, S. E. Webber et al. · Proceedings of the National Academy of Sciences · 1999 · 318 citations · Full text

Life Sciences, Biochemistry, Biology +17

A rapid approximation to the solvent accessible surface areas of atoms

Winnfried Hasel, Thomas F. Hendrickson, W. Clark Still · Tetrahedron Computer Methodology · 1988 · 301 citations

Natural Sciences, Chemistry, Physics +14

Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer

Matthew T. Burger, Sabina Pecchi, Allan S. Wagman et al. · ACS Medicinal Chemistry Letters · 2011 · 251 citations · Full text

Pharmacy, Oncology, Pharmacology +13