Juan‐Carlos Valderramos

Decreasing<i>pfmdr1</i>Copy Number in<i>Plasmodium falciparum</i>Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin

Amar Bir Singh Sidhu, Anne‐Catrin Uhlemann, Juan‐Carlos Valderramos et al. · The Journal of Infectious Diseases · 2006 · 394 citations · Full text

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

Min Yu, T. R. Santha Kumar, Louis J. Nkrumah et al. · Cell Host & Microbe · 2008 · 312 citations · Full text

Biology, Biosynthesis, Key Role +11

Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives

Joel S. Freundlich, John W. Anderson, Dimitri Sarantakis et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 76 citations · Full text

Biological Activity, 4′-Substituted Triclosan Derivatives, Medicinal Chemistry +11

X-ray Structural Analysis of Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase as a Pathway toward the Optimization of Triclosan Antimalarial Efficacy

Joel S. Freundlich, Feng Wang, Han-Chun Tsai et al. · Journal of Biological Chemistry · 2007 · 73 citations · Full text

Biochemistry, Triclosan Antimalarial Efficacy, Medicine +13

Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2′-Substituted triclosan derivatives

Joel S. Freundlich, Min Yu, Edinson Lucumi et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 54 citations · Full text

Biological Activity, Medicinal Chemistry, Biochemistry +9