Sascha C. Hughan

PI 3-kinase p110β: a new target for antithrombotic therapy

Shaun P. Jackson, Simone M. Schoenwaelder, Isaac Goncalves et al. · Nature Medicine · 2005 · 589 citations

Medicine, Molecular Medicine, Pharmacology +15

Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins

Ángel Galindo García, S. Prabhakar, Sascha C. Hughan et al. · Blood · 2003 · 171 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Platelet endothelial cell adhesion molecule-1 is a negative regulator of platelet-collagen interactions

Karen L. Jones, Sascha C. Hughan, Sacha M. Dopheide et al. · Blood · 2001 · 130 citations

Medicine, Cell Biology, Molecular Biology +16

Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin αIIbβ3

Cindy L. Yap, Karen E. Anderson, Sascha C. Hughan et al. · Blood · 2002 · 122 citations

Life Sciences, Biochemistry, Cell Biology +17

The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells

Yuping Yuan, Suhasini Kulkarni, Philippe Ulsemer et al. · Journal of Biological Chemistry · 1999 · 118 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17