Arunkumar Manoharan

Chemical inhibitors of CYP450 enzymes in liver microsomes: combining selectivity and unbound fractions to guide selection of appropriate concentration in phenotyping assays

Ramakrishna Nirogi, Veera Raghava Chowdary Palacharla, Venkatesham Uthukam et al. · Xenobiotica · 2014 · 36 citations

Medicine, Pharmacokinetics, Pharmacology +16

Quantitative<i>in vitro</i>phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims

Veera Raghava Chowdary Palacharla, Ramakrishna Nirogi, Venkatesham Uthukam et al. · Xenobiotica · 2017 · 18 citations · Full text

Medicine, Biochemistry, Pharmacology +16

Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro – in vivo extrapolation of hepatic clearance

Veera Raghava Chowdary Palacharla, Venkatesham Uthukam, Arunkumar Manoharan et al. · European Journal of Pharmaceutical Sciences · 2017 · 15 citations

Pharmacy, Biochemistry, Pharmacology +17

Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction

Ramakrishna Nirogi, Veera Raghava Chowdary Palacharla, Abdul Rasheed Mohammed et al. · Chemico-Biological Interactions · 2015 · 13 citations

Medicine, Pharmacokinetics, Pharmacology +17

Mechanistic evaluation of tapentadol in reducing the pain perception using in-vivo brain and spinal cord microdialysis in rats

Vijay Benade, Ramakrishna Nirogi, Gopinadh Bhyrapuneni et al. · European Journal of Pharmacology · 2017 · 11 citations

Nursing, Neuroscience, Pharmacology +16