Y. Akahane

Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources

Hiroaki Okamoto, Yuichi Sugiyama, S Okada et al. · Journal of General Virology · 1992 · 1.3K citations

Life Sciences, Infectious Diseases, Microbiology +13

Detection of hepatitis C virus RNA by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5'-noncoding region.

Hiroaki Okamoto, S Okada, Y Sugiyama et al. · PubMed · 1990 · 549 citations

Life Sciences, Microbiology, Molecular Biology +16

Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen

Hiroaki Okamoto, S Yotsumoto, Y. Akahane et al. · Journal of Virology · 1990 · 518 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +16

Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen

Hiroaki Okamoto, Fumio Tsuda, Y. Akahane et al. · Journal of Virology · 1994 · 489 citations · Full text

Life Sciences, Microbiology, Molecular Biology +13

Naturally occurring escape mutants of hepatitis B virus with various mutations in the S gene in carriers seropositive for antibody to hepatitis B surface antigen

Kayoko Yamamoto, Minoru Horikita, Fumio Tsuda et al. · Journal of Virology · 1994 · 306 citations · Full text

Life Sciences, Genetics, Molecular Biology +15