Mary C. Betlach

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

Francisco Bolívar, Raymond L. Rodriguez, Patricia J. Greene et al. · Gene · 1977 · 3.9K citations

Life Sciences, Biotechnology, Genetic Engineering +9

Construction and characterization of new cloning vehicles I. Ampicillin-resistant derivatives of the plasmid pMB9

Francisco Bolívar, Raymond L. Rodriguez, Mary C. Betlach et al. · Gene · 1977 · 1.1K citations

Life Sciences, Biotechnology, Molecular Genetics +12

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel “unnatural” natural products

Robert McDaniel, Arinthip Thamchaipenet, Claes Gustafsson et al. · Proceedings of the National Academy of Sciences · 1999 · 461 citations

Engineering, Biological Engineering, Biotechnology +17

Protein expression in E. coli minicells by recombinant plasmids

Richard B. Meagher, Robert C. Tait, Mary C. Betlach et al. · Cell · 1977 · 354 citations

Life Sciences, Microbiology, Molecular Biology +15

A general method for the purification of restriction enzymes

Patricia J. Greene, Herbert L. Heyneker, Francisco Bolívar et al. · Nucleic Acids Research · 1978 · 314 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15