Paul S. Nelson

Oligonucleotide labeling methods 3. Direct labeling of oligonucleotides employing a novel, non-nucleosidic, 2-aminobutyl-1,3-propanediol backbone

Paul S. Nelson, Mark A. Kent, Sylvester Muthini · Nucleic Acids Research · 1992 · 85 citations · Full text

Bioorganic Chemistry, Molecular Biology, Repetitive Coupling Cycles +16

Natural poly-histidine affinity tag for purification of recombinant proteins on cobalt(II)-carboxymethylaspartate crosslinked agarose

Grigoriy Cħaga, Dmitry E. Bochkariov, George G. Jokhadze et al. · Journal of Chromatography A · 1999 · 76 citations

Protein Chemistry, Recombinant Proteins, Engineering +7

Immobilized metal ion affinity chromatography on Co²⁺‐carboxymethylaspartate–agarose Superflow, as demonstrated by one‐step purification of lactate dehydrogenase from chicken breast muscle

Jennifer Hopp, Paul S. Nelson · Biotechnology and Applied Biochemistry · 1999 · 71 citations

Derivative Peptides, Purification Tag, Biochemistry +15

A new and versatile reagent for incorporating multiple primary aliphatic amines into synthetic oligonucleotides

Paul S. Nelson, Rivka Sherman‐Gold, Roy Leon · Nucleic Acids Research · 1989 · 69 citations · Full text

Bioorganic Chemistry, Engineering, Molecular Biology +17

Bifunctional oligonucleotide probes synthesized using a novel CPG support are able to detect single base pair mutations

Paul S. Nelson, Roy A. Frye, Edison Liu · Nucleic Acids Research · 1989 · 62 citations · Full text

Molecular Biology, Nucleic Acid Amplification Test, Novel Cpg Support +16