John W. Wong

The Evolution of an Amine Dehydrogenase Biocatalyst for the Asymmetric Production of Chiral Amines

Michael J. Abrahamson, John W. Wong, Andreas S. Bommarius · Advanced Synthesis & Catalysis · 2013 · 149 citations

Life Sciences, Biochemistry, Biotechnology +15

Highly Enantioselective Reduction of a Small Heterocyclic Ketone: Biocatalytic Reduction of Tetrahydrothiophene-3-one to the Corresponding (<i>R</i>)-Alcohol

Jack Liang, Emily C. Mundorff, Rama Voladri et al. · Organic Process Research & Development · 2009 · 132 citations

Engineering, Chemical Engineering, Chemistry +17

Development of a Concise, Asymmetric Synthesis of a Smoothened Receptor (SMO) Inhibitor: Enzymatic Transamination of a 4-Piperidinone with Dynamic Kinetic Resolution

Zhihui Peng, John W. Wong, Eric C. Hansen et al. · Organic Letters · 2014 · 102 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Chemoenzymatic Asymmetric Synthesis of Pregabalin Precursors via Asymmetric Bioreduction of β-Cyanoacrylate Esters Using Ene-Reductases

Christoph K. Winkler, Dorina Clay, Simon B. Davies et al. · The Journal of Organic Chemistry · 2013 · 91 citations · Full text

Engineering, Biochemistry, Medicinal Chemistry +17

Use of Enzymes in the Manufacture of Active Pharmaceutical Ingredients—A Science and Safety-Based Approach To Ensure Patient Safety and Drug Quality

Andrew S. Wells, Gregory L. Finch, Peter C. Michels et al. · Organic Process Research & Development · 2012 · 75 citations

Life Sciences, Biotechnology, Pharmaceutical Biotechnology +12