Emma Baston

Monoclonal TCR-redirected tumor cell killing

Nathaniel Liddy, Giovanna Bossi, Katherine J. Adams et al. · Nature Medicine · 2012 · 312 citations

Cancer Immunosurveillance, Medicine, Tumor Immunity +3

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide‐MHC without increasing apparent cross‐reactivity

Steven M. Dunn, P.J. Rizkallah, Emma Baston et al. · Protein Science · 2006 · 110 citations · Full text

Adaptive Immune System, Immunology, Immunodominance +17

Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy

Marine C. C. Raman, P.J. Rizkallah, Ruth Simmons et al. · Scientific Reports · 2016 · 99 citations · Full text

Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry

Malkit Sami, P.J. Rizkallah, Steve M. Dunn et al. · Protein Engineering Design and Selection · 2007 · 63 citations

TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide–HLA Complex

C.H. Coles, Rachel M. Mulvaney, S. Malla et al. · The Journal of Immunology · 2020 · 54 citations · Full text