Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT₃ Receptor Agonists:  Synthesis, Further Structure−Activity Relationships, and Biological Studies

Giuseppe Campiani, Elena Morelli, Sandra Gemma, +12

Journal of Medicinal Chemistry

Caspase‐3 is not essential for DNA fragmentation in MCF‐7 cells during apoptosis induced by the pyrrolo‐1,5‐benzoxazepine, PBOX‐6

Margaret M. Mc Gee, Edel M. Hyland, Giuseppe Campiani, +3

FEBS Letters

Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors. Further SAR Studies and Identification of a Novel Orally Bioavailable Hydrazine-Based Antiviral Agent

Giuseppe Campiani, Francesca Aiello, Monica Fabbrini, +18

Journal of Medicinal Chemistry

Oral BioavailabilityAntiviral DrugChemical BiologyMedicinal ChemistryAntiviral Drug Development +14

Synthesis and Pharmacological Evaluation of Potent and Highly Selective D₃ Receptor Ligands:  Inhibition of Cocaine-Seeking Behavior and the Role of Dopamine D₃/D₂ Receptors

Giuseppe Campiani, Stefania Butini, Francesco Trotta, +12

Journal of Medicinal Chemistry

Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands

Giuseppe Campiani, Vito Nacci, Isabella Fiorini, +11

Journal of Medicinal Chemistry

Drug TargetPbr LigandsOrganic ChemistryPharmacotherapyChemistry +19

Discovery of a New Class of Potential Multifunctional Atypical Antipsychotic Agents Targeting Dopamine D₃and Serotonin 5-HT_1Aand 5-HT_2AReceptors: Design, Synthesis, and Effects on Behavior

Stefania Butini, Sandra Gemma, Giuseppe Campiani, +19

Journal of Medicinal Chemistry

Design, Synthesis, and Structure–Activity Relationship Studies of 4-Quinolinyl- and 9-Acrydinylhydrazones as Potent Antimalarial Agents

Caterina Fattorusso, Giuseppe Campiani, Gagan Kukreja, +17

Journal of Medicinal Chemistry

Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663

Giovanni Maga, Sandra Gemma, Caterina Fattorusso, +11

Biochemistry

Novel and Highly Potent 5-HT₃ Receptor Agonists Based on a Pyrroloquinoxaline Structure

Giuseppe Campiani, Andrea Cappelli, Vito Nacci, +9

Journal of Medicinal Chemistry

Pyrrolo[1,3]benzothiazepine-Based Serotonin and Dopamine Receptor Antagonists. Molecular Modeling, Further Structure−Activity Relationship Studies, and Identification of Novel Atypical Antipsychotic Agents

Giuseppe Campiani, Stefania Butini, Caterina Fattorusso, +21

Journal of Medicinal Chemistry