Jeffrey W. Gross

Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

Hongfeng Deng, Heather P. O’Keefe, Christopher P. Davie et al. · Journal of Medicinal Chemistry · 2012 · 147 citations · Full text

Drug Target, Complex Mixtures, Molecular Biology +21

Toward a Structural Understanding of the Dehydratase Mechanism

S.T.M. Allard, Konstantinos Beis, Marie‐France Giraud et al. · Structure · 2002 · 101 citations · Full text

Biochemistry, Protein Folding, Dehydratase Mechanism +4

Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase

Reema K. Thalji, J. Jeffrey McAtee, Svetlana Belyanskaya et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 64 citations · Full text

Soluble Epoxide Hydrolase, Medicinal Chemistry, Biochemistry +5

Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode

Michael Kranz, Michael Wall, Brian Evans et al. · Bioorganic & Medicinal Chemistry · 2009 · 63 citations · Full text

Molecular Recognition, Medicinal Chemistry, Drug Target +10

Characterization of Enzymatic Processes by Rapid Mix−Quench Mass Spectrometry:  The Case of dTDP-glucose 4,6-Dehydratase

Jeffrey W. Gross, Adrian D. Hegeman, Martha M. Vestling et al. · Biochemistry · 2000 · 51 citations

Aldo-keto Reductase, Glycobiology, Biological Mass Spectrometry +18