S R Tyagi

Sphinganine effects on chemoattractant-induced diacylglycerol generation, calcium fluxes, superoxide production, and on cell viability in the human neutrophil. Delivery of sphinganine with bovine serum albumin minimizes cytotoxicity without affecting inhibition of the respiratory burst.

J. David Lambeth, D N Burnham, S R Tyagi · Journal of Biological Chemistry · 1988 · 118 citations · Full text

Sphinganine Effects, Immunology, Cell Death +20

Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst.

S R Tyagi, Minoru Tamura, D N Burnham et al. · Journal of Biological Chemistry · 1988 · 101 citations · Full text

Cyclic AMP-elevating agents block chemoattractant activation of diradylglycerol generation by inhibiting phospholipase D activation

S R Tyagi, Susan C. Olson, D N Burnham et al. · Journal of Biological Chemistry · 1991 · 77 citations · Full text

On the Biological Occurrence and Regulation of 1-Acyl and 1-O-Alkyl-diradylglycerols in Human Neutrophils

S R Tyagi, D N Burnham, J. David Lambeth · Journal of Biological Chemistry · 1989 · 58 citations · Full text

Altered diacylglycerol level and metabolism in neutrophils from patients with localized juvenile periodontitis

S R Tyagi, David J. Uhlinger, J. David Lambeth et al. · Infection and Immunity · 1992 · 49 citations · Full text

Inflammation, Periodontology, Localized Juvenile Periodontitis +13