Concepedia

Jacob B. Hirdler

JB

Statistics

Publications

5

Citations

135

H-Index

5

Active since

2021

Affiliations

Mayo Clinic in Arizona(Current)

Mayo Clinic

Mayo Clinic in Florida

WinnMed

Mayo Clinic Hospital

Jacob B. Hirdler is an author at Mayo Clinic in Arizona specializing in oncology, programmed cell death protein 1 (pd-1) pathway, and t cell biology.

Publications per year

2021–2025

5

Publications

5

NKG7 Is a T-cell–Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy

Ti Wen, Whitney Barham, Ying Li et al. · Cancer Immunology Research · 2021 · 84 citations · Full text

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A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration–Approved PD-1 and PD-L1 Inhibitors

Whitney Barham, Michelle A. Hsu, Xin Liu et al. · ImmunoHorizons · 2023 · 15 citations · Full text

, , +17

Lysosomal NKG7 restrains mTORC1 activity to promote CD8+ T cell durability and tumor control

Hyoungjun Ham, Jacob B. Hirdler, Daniel Bihnam et al. · Nature Communications · 2025 · 15 citations · Full text

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Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8 <sup>+</sup> T cells via ME1 up-regulation

Joanina K. Gicobi, Zhiming Mao, Grace DeFranco et al. · Science Advances · 2023 · 11 citations · Full text

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Understanding Suboptimal Response to Immune Checkpoint Inhibitors

Mojun Zhu, Henan Zhang, Katrina S. Pedersen et al. · Advanced Biology · 2022 · 10 citations

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