Y Sugiyama

Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.

Y. Naritomi, Shigeyuki Terashita, Sumihisa Kimura et al. · PubMed · 2001 · 317 citations

Physiologically-based Pharmacokinetic Modeling, Cytochrome P450 Metabolism, Bioanalysis +21

Identification of Tissues Responsible for the Conjugative Metabolism of Liquiritigenin in Rats: An Analysis Based on Metabolite Kinetics.

Hisafumi Shimamura, Hiroshi Suzuki, M Hanano et al. · Biological and Pharmaceutical Bulletin · 1993 · 30 citations · Full text

Energy Metabolism, Metabolite Kinetics, Biochemistry +15

Carrier-Mediated Active Transport of the Glucuronide and Sulfate of 6-Hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into Rat Liver: Quantitative Comparison of Permeability in Isolated Hepatocytes, Perfused Liver and Liver in Vivo

Osamu Takenaka, Hiroshi Suzuki, Y Sugiyama · Journal of Pharmacology and Experimental Therapeutics · 1997 · 24 citations

Effect of Sulfadimethoxine on Thiopental Distribution and Elimination in Rats

Hsiu‐Ying Yu, Yasufumi Sawada, Y Sugiyama et al. · Journal of Pharmaceutical Sciences · 1981 · 19 citations

Pharmacological Study, Biochemistry, Medicine +9