Margit Kapás

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

István Gyertyán, Béla Kiss, Katalin Sághy et al. · Neurochemistry International · 2011 · 147 citations

Medicine, Pharmacology, Psychiatry +13

Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO

Ragy R. Girgis, Mark Slifstein, Deepak Cyril D’Souza et al. · Psychopharmacology · 2016 · 126 citations · Full text

Medicine, Pharmacology, Psychiatry +17

Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

Éva Ágai-Csongor, György Domány, Katalin Nógrádi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 92 citations · Full text

Medicine, Pharmacology, Psychiatry +12

Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment)

Tadakatsu Nakamura, Tomoko Kubota, Atsushi Iwakaji et al. · Drug Design Development and Therapy · 2016 · 91 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

István Gyertyán, Katalin Sághy, Judit Laszy et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 55 citations

Medicine, Medicinal Chemistry, Pharmacology +14