Julie Izzo

Co-occurring Genomic Alterations Define Major Subsets of <i>KRAS</i> -Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

Ferdinandos Skoulidis, Lauren A. Byers, Lixia Diao et al. · Cancer Discovery · 2015 · 916 citations · Full text

Medicine, Immunology, Oncology +17

The Crosstalk of mTOR/S6K1 and Hedgehog Pathways

Yan Wang, Qingqing Ding, Chia-Jui Yen et al. · Cancer Cell · 2012 · 349 citations · Full text

Life Sciences, Biology, Molecular Biology +10

Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport

Jennifer Sims‐Mourtada, Julie Izzo, Jaffer A. Ajani et al. · Oncogene · 2007 · 215 citations

Medicine, Pharmacology, Cancer Pharmacology +11

Hypoxia Triggers Hedgehog-Mediated Tumor–Stromal Interactions in Pancreatic Cancer

Taly R. Spivak-Kroizman, Galen Hostetter, Richard G. Posner et al. · Cancer Research · 2013 · 209 citations · Full text

Medicine, Cancer Biology, Oncology +17

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer

Vassiliki A. Papadimitrakopoulou, Ignacio I. Wistuba, Anne S. Tsao et al. · Journal of Clinical Oncology · 2016 · 182 citations

Medicine, Oncology, Pharmacology +17