IgE Enhances Mouse Mast Cell FcεRI Expression In Vitro and In Vivo: Evidence for a Novel Amplification Mechanism in IgE-dependent Reactions

Masao Yamaguchi, Chris S. Lantz, Hans C. Oettgen, +5

The Journal of Experimental Medicine

Ri ExpressionMast Cell DisorderImmunologyImmune RegulationImmunologic Mechanism +16

Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis.

Ichiro Miyajima, David Dombrowicz, Thomas R. Martin, +3

Journal of Clinical Investigation

AsthmaLung InflammationMast Cell DisorderImmunologyCell Death +17

Absence of Fc epsilonRI alpha chain results in upregulation of Fc gammaRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc epsilonRI and Fc gammaRIII for limiting amounts of FcR beta and gamma chains.

David Dombrowicz, Véronique Flamand, Ichiro Miyajima, +3

Journal of Clinical Investigation

Gamma ChainsMast Cell DisorderImmunologyImmune RegulationImmunologic Mechanism +16

Immune Sensitization in the Skin Is Enhanced by Antigen-Independent Effects of IgE

Paul Bryce, Mendy Miller, Ichiro Miyajima, +3

Immunity

InflammationImmune SensitizationAllergyAntigen-independent EffectsAtopic Dermatitis +12

IgE regulates mouse basophil Fc epsilon RI expression in vivo

Chris S. Lantz, Masao Yamaguchi, Hans C. Oettgen, +4

The Journal of Immunology

Chronic HCV infection was associated with severe insulin resistance and mild atherosclerosis: a population-based study in an HCV hyperendemic area

Ichiro Miyajima, Takumi Kawaguchi, Ako Fukami, +5

Journal of Gastroenterology

Metabolic SyndromeViral PersistenceHepatologyHepatitis CSevere Insulin Resistance +9

An analysis of drug-induced liver injury, which showed histological findings similar to autoimmune hepatitis

Akiko Hisamochi, Masayoshi Kage, Tatsuya Ide, +8

Journal of Gastroenterology

HepatologyAutoimmune DiseaseMedicineLiver PhysiologyImmunology +12

A Randomized Study of Extended Treatment With Peginterferon α-2b Plus Ribavirin Based on Time to HCV RNA Negative–Status in Patients With Genotype 1b Chronic Hepatitis C

Tatsuya Ide, Teruko Hino, Kei Ogata, +4

The American Journal of Gastroenterology

The incidence of hepatocellular carcinoma in patients with chronic hepatitis C after interferon treatment.

Ichiro Miyajima, M Sata, Ryukichi Kumashiro, +4

Oncology Reports

Effect of interferon treatment on serum 2?,5?-oligoadenylate synthetase levels in hepatitis C-infected patients

Shiro Murashima, Ryukichi Kumashiro, Tatsuya Ide, +7

Journal of Medical Virology