Yong-Seok Heo

Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy

Ju‐Yeun Lee, Hyun Tae Lee, Woo‐Ri Shin et al. · Nature Communications · 2016 · 283 citations · Full text

Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules

B.-J. Sung, Kwang Yeon Hwang, Young Ho Jeon et al. · Nature · 2003 · 270 citations

Molecular Pharmacology, Catalytic Domain, Human Phosphodiesterase 5 +10

Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125

Yong-Seok Heo, Su Kyoung Kim, Chang Il Seo et al. · The EMBO Journal · 2004 · 264 citations · Full text

Selective Inhibition, Protein Chemistry, Protein Function +11

Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab

Hyun Tae Lee, Ju‐Yeun Lee, Heejin Lim et al. · Scientific Reports · 2017 · 231 citations · Full text

Immunology, Pd-l1 Interactions, Pharmacotherapy +19

Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activity

Kyung‐Mi Lee, Ki Won Lee, Sung Keun Jung et al. · Biochemical Pharmacology · 2010 · 126 citations · Full text

Signal Transduction, Chemoprevention Strategy, Signaling Pathway +10