New Helper Cells and Matched Early Region 1-Deleted Adenovirus Vectors Prevent Generation of Replication-Competent Adenoviruses

Frits J. Fallaux, A. Bout, Ietje van der Velde, +9

Human Gene Therapy

Viral ReplicationNew Helper CellsMolecular VirologyReplication-competent AdenovirusesNatural Sciences +12

Single chain Ig/γ gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity

M. E. M. Weijtens, Ralph A. Willemsen, Dinko Valerio, +2

The Journal of Immunology

Overexpression of the <i>MDRL</i> gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin‐A

Kees Nooter, Pieter Sonneveld, Robert Oostrum, +3

International Journal of Cancer

Mixed-phenotype Acute LeukemiaImmunologyPathologyPharmacotherapyTumor Biology +14

Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death

Alexandra A. J. Migchielsen, Marco L. Breuer, Marian A. van Roon, +7

Nature Genetics

InflammationHepatologyAdenosine–deaminase–deficient Mice DieLiver PhysiologyApoptosis +8

Human mesenchymal stem cells ectopically expressing full-length dystrophin can complement Duchenne muscular dystrophy myotubes by cell fusion

Manuel A.F.V. Gonçalves, Antoine A.F. de Vries, Maarten Holkers, +5

Human Molecular Genetics

In vitro and in vivo gene transfer to pulmonary cells mediated by cationic liposomes

Elisabetta Fortunati, A. Bout, Maria Antonia Zanta, +2

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Pulmonary CellsLung DepositionCationic LiposomesImmunologyGene Delivery +4

Highly Efficient Targeted Transduction of Undifferentiated Human Hematopoietic Cells by Adenoviral Vectors Displaying Fiber Knobs of Subgroup B

Shoshan Knaän‐Shanzer, Ietje van der Velde, Menzo Havenga, +3

Human Gene Therapy

MedicineSubgroup BImmunologyHematologyBlood Cell +12

Feasibility of Adenovirus-Mediated Nonsurgical Synovectomy in Collagen-Induced Arthritis-Affected Rhesus Monkeys

Paulien H. Goossens, G. J. Schouten, Bert A. ‘t Hart, +6

Human Gene Therapy

ImmunologyPathologyAdenovirus-mediated Nonsurgical SynovectomySurgeryTk Gene Therapy +14

Lung Gene Therapy: <i>In Vivo</i> Adenovirus-Mediated Gene Transfer to Rhesus Monkey Airway Epithelium

A. Bout, Michel Perricaudet, Gary B. Baskin, +4

Human Gene Therapy

Endowing Human Adenovirus Serotype 5 Vectors with Fiber Domains of Species B Greatly Enhances Gene Transfer into Human Mesenchymal Stem Cells

Shoshan Knaän‐Shanzer, Marloes J.M. van de Watering, Ietje van der Velde, +3

Stem Cells

ImmunologyEgfp LevelFiber DomainsRegenerative MedicineBone Morphogenic Protein +15