The G/G Genotype of a Resistin Single-Nucleotide Polymorphism at −420 Increases Type 2 Diabetes Mellitus Susceptibility by Inducing Promoter Activity through Specific Binding of Sp1/3

Haruhiko Osawa, Kazuya Yamada, Hiroshi Onuma, +12

The American Journal of Human Genetics

Resistin Single-nucleotide PolymorphismMetabolic SyndromeGenetic DeterminantG/g GenotypeDiabetes Epidemiology +9

Plasma Resistin, Associated With Single Nucleotide Polymorphism −420, Is Correlated With Insulin Resistance, Lower HDL Cholesterol, and High-Sensitivity C-Reactive Protein in the Japanese General Population

Haruhiko Osawa, Yasuharu Tabara, Ryuichi Kawamoto, +9

Diabetes Care

Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes

Haruhiko Osawa, Hiroshi Onuma, Masaaki Ochi, +14

Biochemical and Biophysical Research Communications

Metabolic SyndromeGenetic DeterminantResistin Snp-420GeneticsDiabetes +6

Systematic Search for Single Nucleotide Polymorphisms in the Resistin Gene

Haruhiko Osawa, Hiroshi Onuma, Akiko Murakami, +7

Diabetes

Hyperresistinemia Is Associated With Coexistence of Hypertension and Type 2 Diabetes

Yasunori Takata, Haruhiko Osawa, Mie Kurata, +7

Hypertension

HypertensionBlood PressureSerum ResistinObesityMetabolic Syndrome +14

Serum total and high molecular weight adiponectin levels are correlated with the severity of diabetic retinopathy and nephropathy

Kenichi Kato, Haruhiko Osawa, Masaaki Ochi, +8

Clinical Endocrinology

A at Single Nucleotide Polymorphism-358 Is Required for G at -420 to Confer the Highest Plasma Resistin in the General Japanese Population

Hiroshi Onuma, Yasuharu Tabara, Ryoichi Kawamura, +11

PLoS ONE

GeneticsGenetic EpidemiologyHuman PolymorphismMolecular GeneticsImmune-related Gene Polymorphism +17

Frequency of the G/G Genotype of Resistin Single Nucleotide Polymorphism at −420 Appears to Be Increased in Younger-Onset Type 2 Diabetes

Masaaki Ochi, Haruhiko Osawa, Yushi Hirota, +13

Diabetes

Serum resistin is positively correlated with the accumulation of metabolic syndrome factors in type 2 diabetes

Haruhiko Osawa, Masaaki Ochi, Yasuharu Tabara, +10

Clinical Endocrinology

Plasma Resistin Is Associated With Single Nucleotide Polymorphisms of a Possible Resistin Receptor, the Decorin Gene, in the General Japanese Population

Hiroshi Onuma, Yasuharu Tabara, Ryoichi Kawamura, +9

Diabetes

GeneticsHuman PolymorphismAdipokinesDrug ResistanceMetabolic Syndrome +14