Tomoyo Okada

Merlin/ <i>NF-2</i> mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane

Tomoyo Okada, Miguel A. López-Lago, Filippo G. Giancotti · The Journal of Cell Biology · 2005 · 191 citations · Full text

Loss of the Tumor Suppressor Gene <i>NF2</i>, Encoding Merlin, Constitutively Activates Integrin-Dependent mTORC1 Signaling

Miguel A. López-Lago, Tomoyo Okada, Miguel Murillo et al. · Molecular and Cellular Biology · 2009 · 184 citations · Full text

Encoding Merlin, Integrin-dependent Mtorc1, Cancer Biology +19

The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling

Tomoyo Okada, Surajit Sinha, Ilaria Esposito et al. · Nature Cell Biology · 2014 · 127 citations · Full text

Signaling Pathway, Cell Regulation, Medicine +10

Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma

Tomoyo Okada, Ann Y. Lee, Li‐Xuan Qin et al. · Cancer Discovery · 2016 · 95 citations · Full text

RA-GEF, a Novel Rap1A Guanine Nucleotide Exchange Factor Containing a Ras/Rap1A-associating Domain, Is Conserved between Nematode and Humans

Yanhong Liao, Ken‐ichi Kariya, Chang‐Deng Hu et al. · Journal of Biological Chemistry · 1999 · 89 citations · Full text