Madeleine S.Q. Kortenhorst

Downregulation of Homologous Recombination DNA Repair Genes by HDAC Inhibition in Prostate Cancer Is Mediated through the E2F1 Transcription Factor

Sushant K. Kachhap, Nadine Rosmus, Spencer J. Collis et al. · PLoS ONE · 2010 · 152 citations · Full text

Life Sciences, Genetics, Oncology +14

Multiple Molecular pathways explain the anti‐proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo

Shabana Shabbeer, Madeleine S.Q. Kortenhorst, Sushant K. Kachhap et al. · The Prostate · 2007 · 79 citations

Medicine, Oncology, Pharmacology +14

Analysis of the genomic response of human prostate cancer cells to histone deacetylase inhibitors

Madeleine S.Q. Kortenhorst, Michel D. Wissing, Ronald Rodríguez et al. · Epigenetics · 2013 · 37 citations · Full text

Medicine, Cancer Biology, Oncology +17

Valproic acid causes dose- and time-dependent changes in nuclear structure in prostate cancer cells <i>in vitro</i> and <i>in vivo</i>

Madeleine S.Q. Kortenhorst, Sumit Isharwal, P. J. van Diest et al. · Molecular Cancer Therapeutics · 2009 · 35 citations · Full text

Medicine, Molecular Biology, Oncology +16

Targeting prostate cancer cell lines with polo‐like kinase 1 inhibitors as a single agent and in combination with histone deacetylase inhibitors

Michel D. Wissing, Janet Mendonca, Madeleine S.Q. Kortenhorst et al. · The FASEB Journal · 2013 · 34 citations · Full text

Medicine, Oncology, Pharmacology +15