Kwang‐Ai Won

Deregulated cyclin E induces chromosome instability

Charles Spruck, Kwang‐Ai Won, Steven I. Reed · Nature · 1999 · 685 citations

Chromatin, Genetics, Chromosome Biology +4

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

Heimo Strohmaier, Charles Spruck, Peter Kaiser et al. · Nature · 2001 · 579 citations

Protein Function, Breast Oncology, Medicine +8

Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases

Fawn Qian, Stefan Engst, Peiwen Yu et al. · Cancer Research · 2009 · 336 citations

Tumor Cell Growth, Novel Inhibitor, Vegf Receptor 2 +16

Characterization of the Activity of the PI3K/mTOR Inhibitor XL765 (SAR245409) in Tumor Models with Diverse Genetic Alterations Affecting the PI3K Pathway

Peiwen Yu, Alexander Laird, Xiangnan Du et al. · Molecular Cancer Therapeutics · 2014 · 77 citations

Pi3k/mtor Inhibitor Xl765, Cancer Biology, Pi3k Pathway +18

The Selective PI3K Inhibitor XL147 (SAR245408) Inhibits Tumor Growth and Survival and Potentiates the Activity of Chemotherapeutic Agents in Preclinical Tumor Models

Paul Foster, Pin P. Hsu, Fawn Qian et al. · Molecular Cancer Therapeutics · 2015 · 54 citations · Full text