Charles Spruck

Deregulated cyclin E induces chromosome instability

Charles Spruck, Kwang‐Ai Won, Steven I. Reed · Nature · 1999 · 685 citations

Chromatin, Genetics, Chromosome Biology +4

Two molecular pathways to transitional cell carcinoma of the bladder.

Charles Spruck, Petra F. Ohneseit, Mirella Gonzalez‐Zulueta et al. · PubMed · 1994 · 605 citations

Cancer Pathology, Pathology, Cancer Biology +16

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

Heimo Strohmaier, Charles Spruck, Peter Kaiser et al. · Nature · 2001 · 579 citations

Protein Function, Breast Oncology, Medicine +8

<i>FBXW7/hCDC4</i> Is a General Tumor Suppressor in Human Cancer

Shahab Akhoondi, Dahui Sun, Natalie von der Lehr et al. · Cancer Research · 2007 · 516 citations

p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade, and stage in bladder cancer.

David Esrig, Charles Spruck, Peter W. Nichols et al. · PubMed · 1993 · 459 citations · Full text