Hernán Pessoa‐Mahana

FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway

Félix A. Urra, Felipe Muñoz, Miguel Córdova‐Delgado et al. · Scientific Reports · 2018 · 66 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor

Javier Romero‐Parra, Jaime Mella, Vittoria Palmieri et al. · European Journal of Medicinal Chemistry · 2016 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation

Félix A. Urra, Miguel Córdova‐Delgado, Michel Lapier et al. · Toxicology and Applied Pharmacology · 2015 · 33 citations · Full text

Life Sciences, Oncology, Pharmacology +15

An ortho-carbonyl substituted hydroquinone derivative is an anticancer agent that acts by inhibiting mitochondrial bioenergetics and by inducing G2/M-phase arrest in mammary adenocarcinoma TA3

Félix A. Urra, Maximiliano Martínez‐Cifuentes, Mario Pavani et al. · Toxicology and Applied Pharmacology · 2013 · 32 citations · Full text

Medicine, Oncology, Pharmacology +12

Effects of 9,10-dihydroxy-4,4-dimethyl-5,8-dihydro-1(4H)-anthracenone derivatives on tumor cell respiration

Ramiro Araya‐Maturana, Wilson Cardona, Bruce K. Cassels et al. · Bioorganic & Medicinal Chemistry · 2006 · 32 citations · Full text

Medicine, Oncology, Pharmacology +13