Günter Harth

Recombinant bacillus Calmette–Guérin (BCG) vaccines expressing the<i>Mycobacterium tuberculosis</i>30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model

Marcus A. Horwitz, Günter Harth, Barbara Jane Dillon et al. · Proceedings of the National Academy of Sciences · 2000 · 434 citations · Full text

A New Vaccine against Tuberculosis Affords Greater Survival after Challenge than the Current Vaccine in the Guinea Pig Model of Pulmonary Tuberculosis

Marcus A. Horwitz, Günter Harth · Infection and Immunity · 2003 · 201 citations · Full text

Glutamine Synthetase GlnA1 Is Essential for Growth of <i>Mycobacterium tuberculosis</i> in Human THP-1 Macrophages and Guinea Pigs

Michael V. Tullius, Günter Harth, Marcus A. Horwitz · Infection and Immunity · 2003 · 173 citations · Full text

Glutamine Synthetase Glna1, Human Thp-1 Macrophages, Pulmonary Tuberculosis +15

Treatment of <i>Mycobacterium tuberculosis</i> with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly- <scp>l</scp> -glutamate/glutamine cell wall structure, and bacterial replication

Günter Harth, Paul C. Zamecnik, Jinyan Tang et al. · Proceedings of the National Academy of Sciences · 2000 · 132 citations · Full text

An Inhibitor of Exported <i>Mycobacterium tuberculosis</i> Glutamine Synthetase Selectively Blocks the Growth of Pathogenic Mycobacteria in Axenic Culture and in Human Monocytes: Extracellular Proteins as Potential Novel Drug Targets

Günter Harth, Marcus A. Horwitz · The Journal of Experimental Medicine · 1999 · 126 citations · Full text

Microbial Pathogens, Immunology, Bacteriology +18