Keith Langley

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

Krisztina M. Zsebo, David A. Williams, E N Geissler et al. · Cell · 1990 · 1.4K citations

Developmental Biology, Signal Transduction, Medicine +9

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

Krisztina M. Zsebo, Jette Wypych, Ian McNiece et al. · Cell · 1990 · 823 citations

Developmental Biology, Medicine, Liver Physiology +9

Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm

B. Jack Longley, Lynda Tyrrell, Shu-Zhuang Lu et al. · Nature Genetics · 1996 · 607 citations

Aggressive Mastocytosis, Somatic Cell Genetics, Mast Cell Disorder +7

Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages.

Ian McNiece, Keith Langley, K M Zsebo · PubMed · 1991 · 438 citations

The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype.

Mindy Tsai, le-Ming Shih, GF Newlands et al. · The Journal of Experimental Medicine · 1991 · 292 citations · Full text

Mast Cell Disorder, Adult Stem Cell, Immunology +23