Denis Roche

Phenome-Wide Association Studies on a Quantitative Trait: Application to TPMT Enzyme Activity and Thiopurine Therapy in Pharmacogenomics

Antoine Neuraz, Laurent Chouchana, Georgia Malamut et al. · PLoS Computational Biology · 2013 · 55 citations · Full text

Medicine, Pharmacology, Medical Genetics +14

Interindividual Variability in Tpmt Enzyme Activity: 10 Years of Experience with Thiopurine Pharmacogenetics and Therapeutic Drug Monitoring

Laurent Chouchana, Céline Narjoz, Denis Roche et al. · Pharmacogenomics · 2014 · 50 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Validation of an Ultra-High Performance Liquid Chromatography Tandem Mass Spectrometric Method for Quantifying Uracil and 5,6-Dihydrouracil in Human Plasma

François Coudoré, Denis Roche, Sandrine Lefeuvre et al. · Journal of Chromatographic Science · 2012 · 38 citations · Full text

Pharmacy, Biochemistry, Analytical Chemistry +16

Elimination of caffeine interference in HPLC determination of urinary nicotine and cotinine.

Nguyen Thi Minh Thuan, Marion Migueres, Denis Roche et al. · Clinical Chemistry · 1989 · 34 citations · Full text

Pharmacy, Toxicology, Analytical Toxicology +13

<b>Post‐prandial metabolism of triglyceride‐rich lipoproteins in non‐insulin‐dependent diabetic patients before and after bezafibrate treatment</b>

N. Attia, Vincent Durlach, Denis Roche et al. · European Journal of Clinical Investigation · 1997 · 27 citations

Medicine, Endocrinology, Internal Medicine +17