Brian Roche

Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: Current recommendations from the Safety Pharmacology Society

D.J. Leishman, Thomas W. Beck, Noël Dybdal et al. · Journal of Pharmacological and Toxicological Methods · 2011 · 103 citations

Medicine, Cardiology, Pharmacology +10

Evaluation of the six-minute walk test in dogs

Kirstin N Boddy, Brian Roche, Denise Saretta Schwartz et al. · American Journal of Veterinary Research · 2004 · 49 citations

Medicine, Cardiology, Veterinary Physiology +16

Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc

Robert L. Hamlin, Charles A. Cruze, Scott W. Mittelstadt et al. · Journal of Pharmacological and Toxicological Methods · 2003 · 47 citations

Medicine, Cardiology, Pharmacology +10

Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: Effects of early versus delayed treatment

Lin Zhao, Brian Roche, Jerry L. Wessale et al. · Life Sciences · 2008 · 34 citations

Medicine, Cardiology, Pharmacology +11

Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As

Eric I. Rossman, Todd Wisialowski, Hugo M. Vargas et al. · Journal of Pharmacological and Toxicological Methods · 2023 · 34 citations

Medicine, Cardiology, Pharmacology +11