B.G. Siim

Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin

Mary S. Kovacs, D J Hocking, James Evans et al. · British Journal of Cancer · 1999 · 73 citations · Full text

Tirapazamine-induced DNA damage measured using the comet assay correlates with cytotoxicity towards hypoxic tumour cells in vitro

B.G. Siim, PL van Zijl · British Journal of Cancer · 1996 · 60 citations · Full text

Dna Damage, Medicine, Comet Assay Correlates +10

Tirapazamine-induced cytotoxicity and DNA damage in transplanted tumors: relationship to tumor hypoxia.

B.G. Siim, Douglas Menke, Mary J. Dorie et al. · PubMed · 1997 · 54 citations

Dna Damage, Radiation Effect, Radiation Exposure +20

Nitro reduction as an electronic switch for bioreductive drug activation.

B.G. Siim, William A. Denny, William R. Wilson · PubMed · 1997 · 53 citations

Bioorganic Chemistry, Chemoprevention Strategy, Aromatic Nitro Groups +18

Synthesis and characterization of aziridine complexes of cobalt(III) and chromium(III) designed as hypoxia-selective cytotoxins. X-ray crystal structure of trans-[Co(Az)4(NO2)2]Br.cntdot.2H2O.cntdot.LiBr

David C. Ware, B.G. Siim, Keith Robinson et al. · Inorganic Chemistry · 1991 · 50 citations

Inorganic Chemistry, Chemical Engineering, Engineering +10