Junfang Zhou

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

Amit C. Nathwani, Edward G. D. Tuddenham, Savita Rangarajan et al. · New England Journal of Medicine · 2011 · 1.8K citations · Full text

Medicine, Hematology, Molecular Medicine +13

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

Amit C. Nathwani, John T. Gray, Catherine Y. Ng et al. · Blood · 2005 · 422 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

Long-term Safety and Efficacy Following Systemic Administration of a Self-complementary AAV Vector Encoding Human FIX Pseudotyped With Serotype 5 and 8 Capsid Proteins

Amit C. Nathwani, Cecilia Rosales, Jenny McIntosh et al. · Molecular Therapy · 2011 · 350 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

Amit C. Nathwani, John T. Gray, Jenny McIntosh et al. · Blood · 2006 · 273 citations · Full text

Medicine, Molecular Medicine, Pharmaceutical Biotechnology +11

Comparison of the ability of adeno-associated viral vectors pseudotyped with serotype 2, 5, and 8 capsid proteins to mediate efficient transduction of the liver in murine and nonhuman primate models

Andrew M. Davidoff, John T. Gray, Catherine Y. Ng et al. · Molecular Therapy · 2005 · 216 citations · Full text

Life Sciences, Molecular Biology, Gene Delivery +14