Hirobumi Takahashi

Sequential radical cyclization, alkoxy-radical fragmentation, and recyclization processes: a novel method for the synthesis of fused cycloheptanones and cyclooctenones from cyclohexanones

Atsushi Nishida, Hirobumi Takahashi, Hiroko Takeda et al. · Journal of the American Chemical Society · 1990 · 74 citations

Sequential Radical Cyclization, Alkoxy-radical Fragmentation, Heterocyclic +11

Discovery of Tetrasubstituted Imidazolines as Potent and Selective Neuropeptide Y Y5 Receptor Antagonists: Reduced Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity and Potent Antiobesity Effect

Nagaaki Sato, Makoto Ando, Shiho Ishikawa et al. · Journal of Medicinal Chemistry · 2009 · 26 citations · Full text

Pharmacotherapy, Tetrasubstituted Imidazolines, Medicinal Chemistry +17

A Novel Class of Cycloalkano[<i>b</i>]pyridines as Potent and Orally Active Opioid Receptor-like 1 Antagonists with Minimal Binding Affinity to the hERG K⁺Channel

Takashi Yoshizumi, Hirobumi Takahashi, Hiroshi Miyazoe et al. · Journal of Medicinal Chemistry · 2008 · 25 citations · Full text

Vivo Antagonism, Molecular Pharmacology, Medicinal Chemistry +14

Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor

Makoto Ando, Nagaaki Sato, Tsuyoshi Nagase et al. · Bioorganic & Medicinal Chemistry · 2009 · 21 citations · Full text

Biochemistry, Pyridone-containing Imidazolines, Medicine +9

Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists

Toshiyuki Takahashi, Yuji Haga, Toshihiro Sakamoto et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 17 citations · Full text

Molecular Pharmacology, Biochemistry, Functional Selectivity +8