W. Schaffner

A rapid, sensitive, and specific method for the determination of protein in dilute solution

W. Schaffner, Charles Weissmann · Analytical Biochemistry · 1973 · 2.5K citations

Protein Chemistry, Engineering, Biochemistry +12

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

Michael Boshart, Friedemann Weber, Gerhard Jahn et al. · Cell · 1985 · 1.2K citations · Full text

Molecular Virology, Pathogenesis, Immunology +9

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.

S M Iguchi-Ariga, W. Schaffner · Genes & Development · 1989 · 557 citations · Full text

Epigenetic Change, Genetics, Dna Methylation +16

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

Rainer Heuchel, Freddy Radtke, Oleg Georgiev et al. · The EMBO Journal · 1994 · 495 citations · Full text

Reductive Stress, Transcriptional Regulation, Biochemistry +8

Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

Freddy Radtke, Rainer Heuchel, Oleg Georgiev et al. · The EMBO Journal · 1993 · 391 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10