Marsel Mesulam

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Céline Bellenguez, Fahri Küçükali, Iris E. Jansen et al. · Nature Genetics · 2022 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims, Sven J. van der Lee, Adam C. Naj et al. · Nature Genetics · 2017 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

Jennifer Gass, Ashley Cannon, Ian R. Mackenzie et al. · Human Molecular Genetics · 2006 · 578 citations

Life Sciences, Genetics, Molecular Genetics +17

Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease

Sebastian Palmqvist, Henrik Zetterberg, Niklas Mattsson et al. · Neurology · 2015 · 387 citations · Full text

Medicine, Neurology, Neuroscience +17

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

Weirui Guo, Yanbo Chen, Xiaohong Zhou et al. · Nature Structural & Molecular Biology · 2011 · 311 citations · Full text

Life Sciences, Neurology, Neuroscience +16